RELATIONSHIP OF BLOOD SUGAR LEVELS WITH MORTALITY IN ACS PATIENT IN RSUD Dr. H. CHASAN BOESOIRIE
DOI:
https://doi.org/10.24269/ijhs.v9i1.10763Abstract
Acute coronary syndrome is a disease process with a collection of symptoms caused by acute myocardial ischemia due to the presence of atherosclerotic plaques. It has become a health problem with the highest mortality rate in the world and high blood glucose levels are associated with poor clinical outcomes and increased risk of death in hospitalised patients. To determine the relationship between blood sugar levels and mortality in patients with acute coronary syndrome in RSUD Dr. H. Chasan Boesoirie in 2018-2023. This type of research is quantitative cross sectional analytical observational with a retrospective approach and using Spearman’s rho test. The sample totalled to 131 samples taken using medical record data with simple random sampling technique. Based on bivariate analysis, p-value = 0.003 (p<0.05) with a correlation coefficient of 0.261 which means there is a relationship between increased blood sugar levels with mortality with a weak positive correlation. There is a relationship between blood sugar levels and mortality, namely the higher the blood sugar level, the higher the mortality
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[7] A. Aprilia, I. Christina, and R. Suzan, “Hubungan Kadar High-Sensitive Troponin I Dengan Major Adverse Cardiovascular Events Pada Pasien Sindroma Koroner Akut,†J. Kedokt. dan Kesehat. Publ. Ilm. Fak. Kedokt. Univ. Sriwij., vol. 10, no. 2, pp. 163–170, 2023, doi: 10.32539/jkk.v10i2.20152.
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[11] M. Ridwan, Yusni, and Nurkhalis, “Analisis Karakteristik Nyeri Dada Pada Pasien Sindroma Koroner Akut di Rumah Sakit Umum Daerah Dr. Zainoel Abidin Banda Aceh,†J. Med. Sci., vol. 1, no. 1, pp. 20–26, 2020, doi: 10.55572/jms.v1i1.5.
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[13] M. D. R. Diputra, I. W. Wita, and W. Aryadana, “Karakteristik Penderita Sindroma Koroner Akut di RSUP Sanglah Denpasar Tahun 2016,†E-Jurnal Med. Udayana, vol. 7, no. 10, pp. 1–10, 2018, [Online]. Available: https://ojs.unud.ac.id/index.php/eum/article/view/42753.
[14] E. Kusumawati et al., “Hubungan Antara Kadar Troponin Dengan Kejadian Major Adverse Cardiovascular Events Pada Pasien Sindrom Koroner Akut Di Rsi Jemursari Surabaya,†pp. 47–52, 2018.
[15] U. Ralapanawa et al., “Epidemiology and risk factors of patients with types of acute coronary syndrome presenting to a tertiary care hospital in Sri Lanka,†BMC Cardiovasc. Disord., vol. 19, no. 1, pp. 1–9, 2019, doi: 10.1186/s12872- 019-1217-x.
[16] M. Muhibbah, A. Wahid, R. Agustina, and O. Illiandri, “Karakteristik Pasien Sindrom Koroner Akut Pada Pasien Rawat Inap Ruang Tulip Di Rsud Ulin Banjarmasin,†Indones. J. Heal. Sci., vol. 3, no. 1, p. 6, 2019, doi: 10.24269/ijhs.v3i1.1567.
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[18] I. Qothi and A. Subagjo, “Profile of Major Risk Factors in Acute Coronary Syndrome (ACS) at Pusat Pelayanan Jantung Terpadu (PPJT) Dr. SoetomoPublic Hospital Surabaya,†Cardiovasc. Cardiometabolic J., pp. 59–72, 2021, doi: 10.2473/ccj.v2i2.2021.59-72.
[19] Syed Mahmood, D. Levy, R. S. Vasan, and T. J. Wang, “The Framingham Heart Study and the Epidemiology of Cardiovascular Diseases: A Historical Perspective,†Lancet, vol. 383, no. 9921,pp. 1933–1945, 2014, doi: 10.1016/S0140- 6736(13)61752-3.The.
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[23] D. Ardiansyah, J. Farizal, and D. Irnameria, “Gambaran Kadar Kreatinin Darah Pada Pasien Penyakit Jantung Koroner Di Ruang Iccu Rsud Dr. M.Yunus Provinsi Bengkulu,†JNPH, vol. 6, no. 2,pp. 14–18, 2018.
[24] I. N. N. Mahmuda, Y. N. Rezki, and W. Priscillah, “Hiperglikemia Sebagai Prediktor Keberhasilan Pengobatan Pasien Dengan Sindrom Koroner Akut Di Rsud X Surakarta,†Biomedika, vol. 10, no. 2, pp. 5–10, 2018, doi: 10.23917/biomedika.v10i2.7023.
[25] G. Maharani Ariaty, R. Widianto Sudjud, and R. Herman Sitanggang, “Angka mortalitas pada pasien yang menjalani bedah pintas koroner berdasar usia, jenis kelamin, left ventricular ejection fraction, cross clamp time, cardio pulmonary bypass time, dan penyakit penyerta,†J. Anestesi Perioper., vol. 5, no. 3, pp. 155–162, 2017.
[26] A. A. A. Firdaus, A. D. Savitri, and D. N. Bistara, “Hubungan Peningkatan Nilai Kadar Creatine Kinase - Mb Mortalitas Pasien Sindroma Koroner Akut (Ska),†vol. 10, no. July, pp. 1–23, 2018.
[27] J. Harrington et al., “Acute Decompensated Heart Failure in the Setting of Acute Coronary Syndrome,†JACC Hear. Fail., vol. 10, no. 6, pp. 404–414, 2022, doi: 10.1016/j.jchf.2022.02.008.
[28] B. Mulyana and U. E. Unggul, “Karakteristik Pasien Sindrom Koroner Akut Di Intensive Cardiac Karakteristik Pasien Sindrom Koroner Akut Di,†no. September, 2022.
[29] S. N. Khalista, A. R. Magdaleni, and D. P. Asmoro, “Hubungan Kadar Troponin T dengan Lama Perawatan dan Mortalitas Selama Perawatan pada Pasien Infark Miokard Akut di RSUD Abdul Wahab Sjahranie Samarinda,†J. Sains dan Kesehat., vol. 2, no. 4, pp. 432–437, 2020
[30] A. Bagai, G. D. Dangas, G. W. Stone, and C. B. Granger, “Reperfusion strategies in acute coronary syndromes,†Circ. Res., vol. 114, no. 12, pp. 1918–1928, 2014,doi: 10.1161/CIRCRESAHA.114.302744.
[31] Y. N. Rezki, “Perbedaan lama rawat inap pada pasien sindrom koroner akut dengan stres hiperglikemia dan tanpa stres hiperglikemia non diabetik di Rsud Dr. Moewardi,†pp. 1–15, 2017.
[32] E. Damanik and N. P. Sipayung, “Prediksi Kadar Glukosa Darah Terhadap Mortalitas Pasien di RSUP H. Adam Malik Medan,†J. Heal. Sci. Physiother., vol. 1, no. 2, pp. 72–78, 2019, doi: 10.35893/jhsp.v1i2.15.
[33] R. De Faria Modenesi et al., “Influence on prognosis and prevalence of stress hyperglycemia in a cohort of patients with acute coronary syndrome,†Rev. Bras. Ter. Intensiva, vol. 24, no. 4, pp. 352–356,2015, doi: 10.1590/S0103-507X2012000400010.
[34] M. A. Orellana-Barrios, J. W. Fries, K. Nugent, and S. Shurmur, “Glycated hemoglobin, admission blood glucose delta, and associated mortality in patients with acute ST-segment elevation myocardial infarction,†Baylor Univ. Med. Cent. Proc., vol. 32, no. 3, pp. 325–330,2019,doi:10.1080/08998280.20191606614.
[35] J. Qian, L. Kuang, L. Che, F. Chen, and X. Liu, “Maximum blood glucose levels during hospitalisation to predict mortality in patients with acute coronary syndrome: A retrospective cohort study,†BMJ Open, vol. 10, no. 12, 2020, doi: 10.1136/bmjopen-2020-042316.
[36] J. El Ouazzani, A. Ghalem, G. El Ouazzani, N. Ismaili, and N. El Ouafi, “Management of hyperglycemia during and in the immediate follow-up of acute coronary syndrome,†J. Saudi Hear. Assoc., vol. 30, no. 2, pp. 113–121, 2018, doi: 10.1016/j.jsha.2017.08.003.
[37] H. Upur et al., “Short and long-term prognosis of admission hyperglycemia in patients with and without diabetes after acute myocardial infarction: a retrospective cohort study,†Cardiovasc. Diabetol., vol. 21, no. 1, pp. 1–11, 2022, doi: 10.1186/s12933-022-01550-4.
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